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Sustained response of three pediatric BRAF(V600E) mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy

Outcomes for children with high-grade gliomas (HGG) remain dismal despite aggressive treatment strategies. The use of targeted therapy for BRAF(V600E) mutated malignancies including HGG is being explored as a potentially well tolerated and effective therapeutic option. The results of adult melanoma...

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Detalles Bibliográficos
Autores principales:	Toll, Stephanie A., Tran, Hung N., Cotter, Jennifer, Judkins, Alexander R., Tamrazi, Benita, Biegel, Jaclyn A., Dhall, Girish, Robison, Nathan J., Waters, Kaaren, Patel, Palak, Cooper, Robert, Margol, Ashley S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355184/ https://www.ncbi.nlm.nih.gov/pubmed/30728904 http://dx.doi.org/10.18632/oncotarget.26560

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