Multiple Placental Infarcts in a Pregnant Woman with Essential Thrombocythemia

Myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia (ET), and primary myelofibrosis, mainly occur in older patients, but have also been reported in younger patients. A “second peak” occurs in female patients in their thirties, particularly in ET; thus, the man...

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Detalles Bibliográficos
Autores principales: Edahiro, Yoko, Ando, Jun, Suzuki, Toshifumi, Fukumura, Yuki, Masuda, Azuchi, Sakayori, Shiori, Takeda, Jun, Maruyama, Yojiro, Makino, Shintaro, Itakura, Atsuo, Komatsu, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355404/
https://www.ncbi.nlm.nih.gov/pubmed/30101937
http://dx.doi.org/10.2169/internalmedicine.1311-18
Descripción
Sumario:Myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia (ET), and primary myelofibrosis, mainly occur in older patients, but have also been reported in younger patients. A “second peak” occurs in female patients in their thirties, particularly in ET; thus, the management of pregnancy is often discussed. We herein present the case of a 33-year-old woman with a high platelet count and multiple placental infarcts during delivery who was subsequently diagnosed with ET. Although there are no worldwide guidelines for the management of MPNs in pregnancy, the risk of thrombosis is markedly increased in these patients, and antithrombotic therapy should be considered.

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