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Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate

Tumoral calcinosis (TC) is a rare benign but aggressive disorder with variable response rates and high recurrence rates despite medical or surgical treatments. We herein report a case of a 28-year-old woman with underlying systemic lupus erythematosus (SLE) who developed diffuse tumoral calcinosis t...

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Autores principales: Hsiao, Ching-Chung, Lee, Cheng-Chia, Chen, Kuan-Hsing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355405/
https://www.ncbi.nlm.nih.gov/pubmed/30146573
http://dx.doi.org/10.2169/internalmedicine.0975-18
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author Hsiao, Ching-Chung
Lee, Cheng-Chia
Chen, Kuan-Hsing
author_facet Hsiao, Ching-Chung
Lee, Cheng-Chia
Chen, Kuan-Hsing
author_sort Hsiao, Ching-Chung
collection PubMed
description Tumoral calcinosis (TC) is a rare benign but aggressive disorder with variable response rates and high recurrence rates despite medical or surgical treatments. We herein report a case of a 28-year-old woman with underlying systemic lupus erythematosus (SLE) who developed diffuse tumoral calcinosis that was successfully treated by lanthanum carbonate. The formation of tumoral calcinosis depends on the supersaturation of calcium and phosphate. Lanthanum carbonate not only has an excellent phosphate-lowering ability but also low gastro-intestinal calcium absorption. It can be considered an effective alternative treatment for tumoral calcinosis if surgical treatment is not feasible.
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spelling pubmed-63554052019-02-01 Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate Hsiao, Ching-Chung Lee, Cheng-Chia Chen, Kuan-Hsing Intern Med Case Report Tumoral calcinosis (TC) is a rare benign but aggressive disorder with variable response rates and high recurrence rates despite medical or surgical treatments. We herein report a case of a 28-year-old woman with underlying systemic lupus erythematosus (SLE) who developed diffuse tumoral calcinosis that was successfully treated by lanthanum carbonate. The formation of tumoral calcinosis depends on the supersaturation of calcium and phosphate. Lanthanum carbonate not only has an excellent phosphate-lowering ability but also low gastro-intestinal calcium absorption. It can be considered an effective alternative treatment for tumoral calcinosis if surgical treatment is not feasible. The Japanese Society of Internal Medicine 2018-08-24 2018-12-15 /pmc/articles/PMC6355405/ /pubmed/30146573 http://dx.doi.org/10.2169/internalmedicine.0975-18 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Hsiao, Ching-Chung
Lee, Cheng-Chia
Chen, Kuan-Hsing
Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate
title Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate
title_full Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate
title_fullStr Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate
title_full_unstemmed Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate
title_short Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate
title_sort successful treatment of tumoral calcinosis by lanthanum carbonate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355405/
https://www.ncbi.nlm.nih.gov/pubmed/30146573
http://dx.doi.org/10.2169/internalmedicine.0975-18
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