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Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate
Tumoral calcinosis (TC) is a rare benign but aggressive disorder with variable response rates and high recurrence rates despite medical or surgical treatments. We herein report a case of a 28-year-old woman with underlying systemic lupus erythematosus (SLE) who developed diffuse tumoral calcinosis t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355405/ https://www.ncbi.nlm.nih.gov/pubmed/30146573 http://dx.doi.org/10.2169/internalmedicine.0975-18 |
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author | Hsiao, Ching-Chung Lee, Cheng-Chia Chen, Kuan-Hsing |
author_facet | Hsiao, Ching-Chung Lee, Cheng-Chia Chen, Kuan-Hsing |
author_sort | Hsiao, Ching-Chung |
collection | PubMed |
description | Tumoral calcinosis (TC) is a rare benign but aggressive disorder with variable response rates and high recurrence rates despite medical or surgical treatments. We herein report a case of a 28-year-old woman with underlying systemic lupus erythematosus (SLE) who developed diffuse tumoral calcinosis that was successfully treated by lanthanum carbonate. The formation of tumoral calcinosis depends on the supersaturation of calcium and phosphate. Lanthanum carbonate not only has an excellent phosphate-lowering ability but also low gastro-intestinal calcium absorption. It can be considered an effective alternative treatment for tumoral calcinosis if surgical treatment is not feasible. |
format | Online Article Text |
id | pubmed-6355405 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-63554052019-02-01 Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate Hsiao, Ching-Chung Lee, Cheng-Chia Chen, Kuan-Hsing Intern Med Case Report Tumoral calcinosis (TC) is a rare benign but aggressive disorder with variable response rates and high recurrence rates despite medical or surgical treatments. We herein report a case of a 28-year-old woman with underlying systemic lupus erythematosus (SLE) who developed diffuse tumoral calcinosis that was successfully treated by lanthanum carbonate. The formation of tumoral calcinosis depends on the supersaturation of calcium and phosphate. Lanthanum carbonate not only has an excellent phosphate-lowering ability but also low gastro-intestinal calcium absorption. It can be considered an effective alternative treatment for tumoral calcinosis if surgical treatment is not feasible. The Japanese Society of Internal Medicine 2018-08-24 2018-12-15 /pmc/articles/PMC6355405/ /pubmed/30146573 http://dx.doi.org/10.2169/internalmedicine.0975-18 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Hsiao, Ching-Chung Lee, Cheng-Chia Chen, Kuan-Hsing Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate |
title | Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate |
title_full | Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate |
title_fullStr | Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate |
title_full_unstemmed | Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate |
title_short | Successful Treatment of Tumoral Calcinosis by Lanthanum Carbonate |
title_sort | successful treatment of tumoral calcinosis by lanthanum carbonate |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355405/ https://www.ncbi.nlm.nih.gov/pubmed/30146573 http://dx.doi.org/10.2169/internalmedicine.0975-18 |
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