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Primary Cardiac Lymphoma: A Lesson Learned from an Unsuccessful Experience

A 79-year-old man was admitted because of complete heart block. Echocardiograms showed an abnormal mass adjacent to the sinus of Valsalva. Subsequent surgical resection was not successful. Despite chemotherapy, the patient died from multiple organ failure. It is important to recognize that approxima...

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Detalles Bibliográficos
Autores principales: Ito, Izumi, Nakaoka, Yoko, Kubokawa, Sho-ichi, Sugane, Hiroki, Kusume, Takahiro, Matsuda, Hideyuki, Imai, Ryu-ichiro, Nishida, Koji, Kubo, Toru, Yamasaki, Naohito, Kitaoka, Hiroaki, Kawai, Kazuya, Hamashige, Naohisa, Doi, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355412/
https://www.ncbi.nlm.nih.gov/pubmed/30146560
http://dx.doi.org/10.2169/internalmedicine.0594-17
Descripción
Sumario:A 79-year-old man was admitted because of complete heart block. Echocardiograms showed an abnormal mass adjacent to the sinus of Valsalva. Subsequent surgical resection was not successful. Despite chemotherapy, the patient died from multiple organ failure. It is important to recognize that approximately 80% of cases of cardiac lymphoma are diffuse large B-cell lymphoma, which is the only malignant neoplasm that may respond well to chemotherapy with rituximab. In order to save patients' lives, the early implementation of chemotherapy with rituximab is critical and should be considered as a therapeutic diagnostic option in select patients.