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A Diagnostic Algorithm To Investigate Pyrazinamide and Ethambutol Resistance in Rifampin-Resistant Mycobacterium tuberculosis Isolates in a Low-Incidence Setting

Phenotypic drug susceptibility testing (DST) for the two first-line tuberculosis drugs ethambutol and pyrazinamide is known to yield unreliable and inaccurate results. In this prospective study, we propose a diagnostic algorithm combining phenotypic DST with Sanger sequencing to inform clinical deci...

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Detalles Bibliográficos
Autores principales:	Andres, Söenke, Gröschel, Matthias I., Hillemann, Doris, Merker, Matthias, Niemann, Stefan, Kranzer, Katharina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Susceptibility
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355586/ https://www.ncbi.nlm.nih.gov/pubmed/30455227 http://dx.doi.org/10.1128/AAC.01798-18

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