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EGF-induced nuclear localization of SHCBP1 activates β-catenin signaling and promotes cancer progression
Aberrant activation of EGFR represents a common event in non-small cell lung carcinoma (NSCLC) and activates various downstream signaling pathways. While EGFR activation of β-catenin signaling was previously reported, the mediating mechanism remains unclear. Our current study found that EGFR activat...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355651/ https://www.ncbi.nlm.nih.gov/pubmed/30177836 http://dx.doi.org/10.1038/s41388-018-0473-z |