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Molecular, Biological and Structural Features of V(L) CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells
Microtubules are important drug targets in tumor cells, owing to their role in supporting and determining the cell shape, organelle movement and cell division. The complementarity-determining regions (CDRs) of immunoglobulins have been reported to be a source of anti-tumor peptide sequences, indepen...
Autores principales: | Girola, Natalia, Resende-Lara, Pedro T., Figueiredo, Carlos R., Massaoka, Mariana H., Azevedo, Ricardo A., Cunha, Rodrigo L. O. R., Polonelli, Luciano, Travassos, Luiz R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355703/ https://www.ncbi.nlm.nih.gov/pubmed/30740361 http://dx.doi.org/10.3389/fonc.2019.00025 |
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