Cargando…
High-fat diet disturbs lipid raft/TGF-β signaling-mediated maintenance of hematopoietic stem cells in mouse bone marrow
Despite recent in vivo data demonstrating that high-fat diet (HFD)-induced obesity leads to major perturbations in murine hematopoietic stem cells (HSC), the direct role of a HFD is not yet completely understood. Here, we investigate the direct impact of a short-term HFD on HSC and hematopoiesis in...
Autores principales: | Hermetet, François, Buffière, Anne, Aznague, Aziza, Pais de Barros, Jean-Paul, Bastie, Jean-Noël, Delva, Laurent, Quéré, Ronan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355776/ https://www.ncbi.nlm.nih.gov/pubmed/30705272 http://dx.doi.org/10.1038/s41467-018-08228-0 |
Ejemplares similares
-
CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts
por: Saint-Paul, Laetitia, et al.
Publicado: (2016) -
High-fat diet intensifies MLL-AF9-induced acute myeloid leukemia through activation of the FLT3 signaling in mouse primitive hematopoietic cells
por: Hermetet, François, et al.
Publicado: (2020) -
Bone marrow-derived extracellular vesicles carry the TGF-β signal transducer Smad2 to preserve hematopoietic stem cells in mice
por: Gautheron, Flavie, et al.
Publicado: (2023) -
Acute lymphoblastic leukemia-derived extracellular vesicles affect quiescence of hematopoietic stem and progenitor cells
por: Georgievski, Aleksandra, et al.
Publicado: (2022) -
CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow
por: Nakamura-Ishizu, Ayako, et al.
Publicado: (2015)