The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model

Buruli ulcer (BU) is an emerging infectious disease that causes disfiguring skin ulcers. The causative agent, Mycobacterium ulcerans, secretes toxin called mycolactone that triggers inflammation and immunopathology. Existing treatments are lengthy and consist of drugs developed for tuberculosis. Her...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Gao, Yamin, Liu, Jianxiong, Tan, Yaoju, Liu, Zhiyong, Chhotaray, Chiranjibi, Jiang, Huofeng, Lu, Zhili, Chiwala, Gift, Wang, Shuai, Makafe, Gaelle, Islam, Md Mahmudul, Hameed, H. M. Adnan, Cai, Xingshan, Wang, Changwei, Li, Xinjie, Tan, Shouyong, Zhang, Tianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355801/
https://www.ncbi.nlm.nih.gov/pubmed/30705268
http://dx.doi.org/10.1038/s41467-019-08464-y

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