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Remodeling of secretory lysosomes during education tunes functional potential in NK cells

Inhibitory signaling during natural killer (NK) cell education translates into increased responsiveness to activation; however, the intracellular mechanism for functional tuning by inhibitory receptors remains unclear. Secretory lysosomes are part of the acidic lysosomal compartment that mediates in...

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Detalles Bibliográficos
Autores principales:	Goodridge, Jodie P., Jacobs, Benedikt, Saetersmoen, Michelle L., Clement, Dennis, Hammer, Quirin, Clancy, Trevor, Skarpen, Ellen, Brech, Andreas, Landskron, Johannes, Grimm, Christian, Pfefferle, Aline, Meza-Zepeda, Leonardo, Lorenz, Susanne, Wiiger, Merete Thune, Louch, William E., Ask, Eivind Heggernes, Liu, Lisa L., Oei, Vincent Yi Sheng, Kjällquist, Una, Linnarsson, Sten, Patel, Sandip, Taskén, Kjetil, Stenmark, Harald, Malmberg, Karl-Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355880/ https://www.ncbi.nlm.nih.gov/pubmed/30705279 http://dx.doi.org/10.1038/s41467-019-08384-x

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