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Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7

Rix7 is an essential type II AAA-ATPase required for the formation of the large ribosomal subunit. Rix7 has been proposed to utilize the power of ATP hydrolysis to drive the removal of assembly factors from pre-60S particles, but the mechanism of release is unknown. Rix7’s mammalian homolog, NVL2 ha...

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Detalles Bibliográficos
Autores principales: Lo, Yu-Hua, Sobhany, Mack, Hsu, Allen L., Ford, Brittany L., Krahn, Juno M., Borgnia, Mario J., Stanley, Robin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355894/
https://www.ncbi.nlm.nih.gov/pubmed/30705282
http://dx.doi.org/10.1038/s41467-019-08373-0