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Fractional laser ablation for the targeted cutaneous delivery of an anti-CD29 monoclonal antibody – OS2966
Monoclonal antibodies targeting cytokines are administered parenterally for the systemic treatment of severe psoriasis. However, systemic exposure to the biologic increases the risk of side-effects including immunosuppression, whereas only a small fraction of the active molecules actually reaches th...
Autores principales: | Lapteva, Maria, del Río-Sancho, Sergio, Wu, Eric, Carbonell, W. Shawn, Böhler, Christof, Kalia, Yogeshvar N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355906/ https://www.ncbi.nlm.nih.gov/pubmed/30705293 http://dx.doi.org/10.1038/s41598-018-36966-0 |
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