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Antibody-free digital influenza virus counting based on neuraminidase activity
There is large demand for a quantitative method for rapid and ultra-sensitive detection of the influenza virus. Here, we established a digital influenza virus counting (DIViC) method that can detect a single virion without antibody. In the assay, a virion is stochastically entrapped inside a femtoli...
Autores principales: | Tabata, Kazuhito V., Minagawa, Yoshihiro, Kawaguchi, Yuko, Ono, Mana, Moriizumi, Yoshiki, Yamayoshi, Seiya, Fujioka, Yoichiro, Ohba, Yusuke, Kawaoka, Yoshihiro, Noji, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355933/ https://www.ncbi.nlm.nih.gov/pubmed/30705374 http://dx.doi.org/10.1038/s41598-018-37994-6 |
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