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Altered hypoxia‐inducible factor–1α (HIF‐1α) signaling contributes to impaired angiogenesis in fetal lambs with persistent pulmonary hypertension of the newborn (PPHN)

Previous studies in adult pulmonary hypertension reported that increased hypoxia‐inducible factor–1α (HIF‐1α) signaling contributes to pulmonary vascular remodeling. However, alterations in endothelial HIF‐1α signaling and its contribution to impaired angiogenesis in persistent pulmonary hypertensio...

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Detalles Bibliográficos
Autores principales: Makker, Kartikeya, Afolayan, Adeleye J., Teng, Ru‐Jeng, Konduri, Girija G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355993/
https://www.ncbi.nlm.nih.gov/pubmed/30706701
http://dx.doi.org/10.14814/phy2.13986