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Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector

Tetracycline is widely used as medicine for disease treatments and additives in animal feeding. Unfortunately, the abuse of tetracycline inevitably causes tetracycline residue in animal-origin foods. Though classical methods can detect tetracycline in high sensitivity and precision, they often rely...

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Autores principales: Li, Jiahao, Wang, Xin, Shan, Yanke, Huang, Huachuan, Jian, Dan, Xue, Liang, Wang, Shouyu, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356201/
https://www.ncbi.nlm.nih.gov/pubmed/30609683
http://dx.doi.org/10.3390/mi10010027
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author Li, Jiahao
Wang, Xin
Shan, Yanke
Huang, Huachuan
Jian, Dan
Xue, Liang
Wang, Shouyu
Liu, Fei
author_facet Li, Jiahao
Wang, Xin
Shan, Yanke
Huang, Huachuan
Jian, Dan
Xue, Liang
Wang, Shouyu
Liu, Fei
author_sort Li, Jiahao
collection PubMed
description Tetracycline is widely used as medicine for disease treatments and additives in animal feeding. Unfortunately, the abuse of tetracycline inevitably causes tetracycline residue in animal-origin foods. Though classical methods can detect tetracycline in high sensitivity and precision, they often rely on huge and expensive setups as well as complicated and time-consuming operations, limiting their applications in rapid and on-site detection. Here, we propose a handheld inkjet printing paper chip based smart tetracycline detector: tetracycline can be determined by inkjet printing prepared paper chip based enzyme-linked immunosorbent assay (ELISA) with the advantages of high sensitivity, excellent specificity and low cost; moreover, a smartphone based paper chip reader and application is designed for automatically determining tetracycline with simple operations, high precision and fast speed. The smart tetracycline detector with a compact size of 154 mm × 80 mm × 50 mm and self-supplied internal power can reach a rather low detection limit of ~0.05 ng/mL, as proved by practical measurements. It is believed the proposed handheld inkjet printing paper chip based smart tetracycline detector is a potential tool in antibiotic sensing for routine uses at home and on-site detection in the field.
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spelling pubmed-63562012019-02-05 Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector Li, Jiahao Wang, Xin Shan, Yanke Huang, Huachuan Jian, Dan Xue, Liang Wang, Shouyu Liu, Fei Micromachines (Basel) Article Tetracycline is widely used as medicine for disease treatments and additives in animal feeding. Unfortunately, the abuse of tetracycline inevitably causes tetracycline residue in animal-origin foods. Though classical methods can detect tetracycline in high sensitivity and precision, they often rely on huge and expensive setups as well as complicated and time-consuming operations, limiting their applications in rapid and on-site detection. Here, we propose a handheld inkjet printing paper chip based smart tetracycline detector: tetracycline can be determined by inkjet printing prepared paper chip based enzyme-linked immunosorbent assay (ELISA) with the advantages of high sensitivity, excellent specificity and low cost; moreover, a smartphone based paper chip reader and application is designed for automatically determining tetracycline with simple operations, high precision and fast speed. The smart tetracycline detector with a compact size of 154 mm × 80 mm × 50 mm and self-supplied internal power can reach a rather low detection limit of ~0.05 ng/mL, as proved by practical measurements. It is believed the proposed handheld inkjet printing paper chip based smart tetracycline detector is a potential tool in antibiotic sensing for routine uses at home and on-site detection in the field. MDPI 2019-01-01 /pmc/articles/PMC6356201/ /pubmed/30609683 http://dx.doi.org/10.3390/mi10010027 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Li, Jiahao
Wang, Xin
Shan, Yanke
Huang, Huachuan
Jian, Dan
Xue, Liang
Wang, Shouyu
Liu, Fei
Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector
title Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector
title_full Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector
title_fullStr Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector
title_full_unstemmed Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector
title_short Handheld Inkjet Printing Paper Chip Based Smart Tetracycline Detector
title_sort handheld inkjet printing paper chip based smart tetracycline detector
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356201/
https://www.ncbi.nlm.nih.gov/pubmed/30609683
http://dx.doi.org/10.3390/mi10010027
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