Cargando…
RNA Editors, Cofactors, and mRNA Targets: An Overview of the C-to-U RNA Editing Machinery and Its Implication in Human Disease
One of the most prevalent epitranscriptomic modifications is RNA editing. In higher eukaryotes, RNA editing is catalyzed by one of two classes of deaminases: ADAR family enzymes that catalyze A-to-I (read as G) editing, and AID/APOBEC family enzymes that catalyze C-to-U. ADAR-catalyzed deamination h...
Autores principales: | Lerner, Taga, Papavasiliou, F. Nina, Pecori, Riccardo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356216/ https://www.ncbi.nlm.nih.gov/pubmed/30591678 http://dx.doi.org/10.3390/genes10010013 |
Ejemplares similares
-
ADAR RNA editing on antisense RNAs results in apparent U-to-C base changes on overlapping sense transcripts
por: Pecori, Riccardo, et al.
Publicado: (2023) -
MultiEditR: The first tool for the detection and quantification of RNA editing from Sanger sequencing demonstrates comparable fidelity to RNA-seq
por: Kluesner, Mitchell G., et al.
Publicado: (2021) -
Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
por: Pecori, Riccardo, et al.
Publicado: (2022) -
Interplay of mRNA capping and transcription machineries
por: Kachaev, Zaur M., et al.
Publicado: (2020) -
Interactions between the HIV-1 Unspliced mRNA and Host mRNA Decay Machineries
por: Toro-Ascuy, Daniela, et al.
Publicado: (2016)