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Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant
Brazil is one of the world’s largest corn producers and is a leader in exportation. Due to intense globalization, corn may be commercialized worldwide and the issue concerning the safety of corn-based products has become a topic of widespread international interest. Dietary exposure evaluation is a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356240/ https://www.ncbi.nlm.nih.gov/pubmed/30634652 http://dx.doi.org/10.3390/toxins11010033 |
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author | Bordini, Jaqueline Gozzi Ono, Mario Augusto Hirozawa, Melissa Tiemi Garcia, Glauco Tironi Vizoni, Edio Ono, Elisabete Yurie Sataque |
author_facet | Bordini, Jaqueline Gozzi Ono, Mario Augusto Hirozawa, Melissa Tiemi Garcia, Glauco Tironi Vizoni, Edio Ono, Elisabete Yurie Sataque |
author_sort | Bordini, Jaqueline Gozzi |
collection | PubMed |
description | Brazil is one of the world’s largest corn producers and is a leader in exportation. Due to intense globalization, corn may be commercialized worldwide and the issue concerning the safety of corn-based products has become a topic of widespread international interest. Dietary exposure evaluation is a relevant criterion for mycotoxin risk assessment. Thus, human exposure to fumonisins were assessed for corn grain and its derivatives (endosperm, cornmeal, and grits; n = 320) sampled from one of the large-scale corn processing plants in Brazil. The total probable daily intake (PDI) for fumonisins in Brazil was 96.9 ng kg(−1) body weight day(−1), which corresponds to 5% of the provisional maximum tolerable daily intake (PMTDI) of 2000 ng kg(−1) b.w. day(−1) for fumonisins. In countries that import Brazilian corn, the total PDI is lower in European countries (from 35.7 to 177 ng kg(−1) b.w. day(−1)) and higher in Angola (1553 ng kg(−1) b.w. day(−1)). Taking into account that dietary exposure in populations in Brazil and importing countries was low, the corn-based products were safe for human consumption regarding fumonisins, even for regions with high corn consumption. |
format | Online Article Text |
id | pubmed-6356240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-63562402019-02-05 Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant Bordini, Jaqueline Gozzi Ono, Mario Augusto Hirozawa, Melissa Tiemi Garcia, Glauco Tironi Vizoni, Edio Ono, Elisabete Yurie Sataque Toxins (Basel) Article Brazil is one of the world’s largest corn producers and is a leader in exportation. Due to intense globalization, corn may be commercialized worldwide and the issue concerning the safety of corn-based products has become a topic of widespread international interest. Dietary exposure evaluation is a relevant criterion for mycotoxin risk assessment. Thus, human exposure to fumonisins were assessed for corn grain and its derivatives (endosperm, cornmeal, and grits; n = 320) sampled from one of the large-scale corn processing plants in Brazil. The total probable daily intake (PDI) for fumonisins in Brazil was 96.9 ng kg(−1) body weight day(−1), which corresponds to 5% of the provisional maximum tolerable daily intake (PMTDI) of 2000 ng kg(−1) b.w. day(−1) for fumonisins. In countries that import Brazilian corn, the total PDI is lower in European countries (from 35.7 to 177 ng kg(−1) b.w. day(−1)) and higher in Angola (1553 ng kg(−1) b.w. day(−1)). Taking into account that dietary exposure in populations in Brazil and importing countries was low, the corn-based products were safe for human consumption regarding fumonisins, even for regions with high corn consumption. MDPI 2019-01-10 /pmc/articles/PMC6356240/ /pubmed/30634652 http://dx.doi.org/10.3390/toxins11010033 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bordini, Jaqueline Gozzi Ono, Mario Augusto Hirozawa, Melissa Tiemi Garcia, Glauco Tironi Vizoni, Edio Ono, Elisabete Yurie Sataque Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant |
title | Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant |
title_full | Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant |
title_fullStr | Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant |
title_full_unstemmed | Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant |
title_short | Safety of Corn and Corn-Based Products Intended for Human Consumption Concerning Fumonisins from a Brazilian Processing Plant |
title_sort | safety of corn and corn-based products intended for human consumption concerning fumonisins from a brazilian processing plant |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356240/ https://www.ncbi.nlm.nih.gov/pubmed/30634652 http://dx.doi.org/10.3390/toxins11010033 |
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