Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism

Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the curr...

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Detalles Bibliográficos
Autores principales: Schindewolf, Craig, Menachery, Vineet D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356267/
https://www.ncbi.nlm.nih.gov/pubmed/30658390
http://dx.doi.org/10.3390/v11010074
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author Schindewolf, Craig
Menachery, Vineet D.
author_facet Schindewolf, Craig
Menachery, Vineet D.
author_sort Schindewolf, Craig
collection PubMed
description Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines.
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spelling pubmed-63562672019-02-05 Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism Schindewolf, Craig Menachery, Vineet D. Viruses Review Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines. MDPI 2019-01-17 /pmc/articles/PMC6356267/ /pubmed/30658390 http://dx.doi.org/10.3390/v11010074 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Schindewolf, Craig
Menachery, Vineet D.
Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism
title Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism
title_full Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism
title_fullStr Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism
title_full_unstemmed Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism
title_short Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism
title_sort middle east respiratory syndrome vaccine candidates: cautious optimism
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356267/
https://www.ncbi.nlm.nih.gov/pubmed/30658390
http://dx.doi.org/10.3390/v11010074
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