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Targeting Proteotoxic Stress in Cancer: A Review of the Role that Protein Quality Control Pathways Play in Oncogenesis

Despite significant advances in cancer diagnostics and therapeutics the majority of cancer unfortunately remains incurable, which has led to continued research to better understand its exceptionally diverse biology. As a result of genomic instability, cancer cells typically have elevated proteotoxic...

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Detalles Bibliográficos
Autores principales: Ho Zhi Guang, Matthew, Kavanagh, Emma L., Dunne, Luke Paul, Dowling, Paul, Zhang, Li, Lindsay, Sinéad, Bazou, Despina, Goh, Chia Yin, Hanley, Cathal, Bianchi, Giada, Anderson, Kenneth C., O’Gorman, Peter, McCann, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356294/
https://www.ncbi.nlm.nih.gov/pubmed/30634515
http://dx.doi.org/10.3390/cancers11010066