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Targeting Proteotoxic Stress in Cancer: A Review of the Role that Protein Quality Control Pathways Play in Oncogenesis
Despite significant advances in cancer diagnostics and therapeutics the majority of cancer unfortunately remains incurable, which has led to continued research to better understand its exceptionally diverse biology. As a result of genomic instability, cancer cells typically have elevated proteotoxic...
Autores principales: | Ho Zhi Guang, Matthew, Kavanagh, Emma L., Dunne, Luke Paul, Dowling, Paul, Zhang, Li, Lindsay, Sinéad, Bazou, Despina, Goh, Chia Yin, Hanley, Cathal, Bianchi, Giada, Anderson, Kenneth C., O’Gorman, Peter, McCann, Amanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356294/ https://www.ncbi.nlm.nih.gov/pubmed/30634515 http://dx.doi.org/10.3390/cancers11010066 |
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