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Very Long-Chain C24:1 Ceramide Is Increased in Serum Extracellular Vesicles with Aging and Can Induce Senescence in Bone-Derived Mesenchymal Stem Cells

Extracellular vesicles (EVs), including exosomes and microvesicles, function in cell-to-cell communication through delivery of proteins, lipids and microRNAs to target cells via endocytosis and membrane fusion. These vesicles are enriched in ceramide, a sphingolipid associated with the promotion of...

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Detalles Bibliográficos
Autores principales:	Khayrullin, Andrew, Krishnan, Priyanka, Martinez-Nater, Luis, Mendhe, Bharati, Fulzele, Sadanand, Liu, Yutao, Mattison, Julie A., Hamrick, Mark W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356348/ https://www.ncbi.nlm.nih.gov/pubmed/30634626 http://dx.doi.org/10.3390/cells8010037

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