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Survivin Splice Variants in Arsenic Trioxide (As(2)O(3))-Induced Deactivation of PI3K and MAPK Cell Signalling Pathways in MCF-7 Cells

Several pathways are deregulated during carcinogenesis but most notably, tumour cells can lose cell cycle control and acquire resistance to apoptosis by expressing a number of anti-apoptotic proteins such as the Inhibitors of Apoptosis Protein (IAP) family of proteins that include survivin, which is...

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Detalles Bibliográficos
Autores principales: Laka, Kagiso, Makgoo, Lilian, Mbita, Zukile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356383/
https://www.ncbi.nlm.nih.gov/pubmed/30646589
http://dx.doi.org/10.3390/genes10010041