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Ocrelizumab Depletes CD20(+) T Cells in Multiple Sclerosis Patients
Ocrelizumab, a humanized monoclonal anti-CD20 antibody, has shown pronounced effects in reduction of disease activity in multiple sclerosis (MS) patients and has recently been approved for the treatment of patients with relapsing MS (RMS) and primary progressive MS (PPMS). CD20 is mainly expressed b...
Autores principales: | Gingele, Stefan, Jacobus, Thais Langer, Konen, Franz Felix, Hümmert, Martin W., Sühs, Kurt-Wolfram, Schwenkenbecher, Philipp, Ahlbrecht, Jonas, Möhn, Nora, Müschen, Lars H., Bönig, Lena, Alvermann, Sascha, Schmidt, Reinhold E., Stangel, Martin, Jacobs, Roland, Skripuletz, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356421/ https://www.ncbi.nlm.nih.gov/pubmed/30597851 http://dx.doi.org/10.3390/cells8010012 |
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