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Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma

Background: Chemotherapeutic resistance of glioblastoma has been attributed to a self-renewing subpopulation, the glioma stem cells (GSCs), which is known to be maintained by the Wnt β−catenin pathway. Our previous findings demonstrated that exogeneous addition of the Wnt antagonist, secreted fizzle...

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Detalles Bibliográficos
Autores principales:	Bhuvanalakshmi, Gurubharathi, Gamit, Naisarg, Patil, Manasi, Arfuso, Frank, Sethi, Gautam, Dharmarajan, Arun, Prem Kumar, Alan, Warrier, Sudha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356444/ https://www.ncbi.nlm.nih.gov/pubmed/30591679 http://dx.doi.org/10.3390/cancers11010025

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