Cargando…
Toxin ζ Reduces the ATP and Modulates the Uridine Diphosphate-N-acetylglucosamine Pool
Toxin ζ expression triggers a reversible state of dormancy, diminishes the pool of purine nucleotides, promotes (p)ppGpp synthesis, phosphorylates a fraction of the peptidoglycan precursor uridine diphosphate-N-acetylglucosamine (UNAG), leading to unreactive UNAG-P, induces persistence in a reduced...
Autores principales: | Moreno-del Álamo, María, Tabone, Mariangela, Muñoz-Martínez, Juan, Valverde, José R., Alonso, Juan C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356619/ https://www.ncbi.nlm.nih.gov/pubmed/30634431 http://dx.doi.org/10.3390/toxins11010029 |
Ejemplares similares
-
Toxin ζ Reversible Induces Dormancy and Reduces the UDP-N-Acetylglucosamine Pool as One of the Protective Responses to Cope with Stress
por: Tabone, Mariangela, et al.
Publicado: (2014) -
Toxin ζ Triggers a Survival Response to Cope with Stress and Persistence
por: Moreno-del Álamo, María, et al.
Publicado: (2017) -
Biosynthesis of uridine diphosphate N‐Acetylglucosamine: An underexploited pathway in the search for novel antibiotics?
por: Wyllie, Jessica A., et al.
Publicado: (2022) -
Role of Toxin ζ and Starvation Responses in the Sensitivity to Antimicrobials
por: Tabone, Mariangela, et al.
Publicado: (2014) -
A Novel Allosteric Inhibitor of the Uridine Diphosphate N-Acetylglucosamine Pyrophosphorylase from Trypanosoma
brucei
por: Urbaniak, Michael D., et al.
Publicado: (2013)