Rac-Mediated Macropinocytosis of Extracellular Protein Promotes Glucose Independence in Non-Small Cell Lung Cancer

Cancer cells can adapt to nutrient poor conditions by rewiring their metabolism and using alternate fuel sources. Identifying these adaptive metabolic pathways may provide novel targets for cancer therapy. Here, we identify a subset of non-small cell lung cancer (NSCLC) cell lines that survive in th...

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Detalles Bibliográficos
Autores principales: Hodakoski, Cindy, Hopkins, Benjamin D., Zhang, Guoan, Su, Taojunfeng, Cheng, Zhe, Morris, Roxanne, Rhee, Kyu Y., Goncalves, Marcus D., Cantley, Lewis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356657/
https://www.ncbi.nlm.nih.gov/pubmed/30609754
http://dx.doi.org/10.3390/cancers11010037

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