Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts

The aim of this study was to determine if increased mortality associated with low levels of serum 25-hydroxyvitamin D (25(OH)D) reflects a causal relationship by using a Mendelian randomisation (MR) approach with genetic variants in the vitamin D synthesis pathway. Individual participant data from t...

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Detalles Bibliográficos
Autores principales: Aspelund, Thor, Grübler, Martin R., Smith, Albert V., Gudmundsson, Elias F., Keppel, Martin, Cotch, Mary Frances, Harris, Tamara B., Jorde, Rolf, Grimnes, Guri, Joakimsen, Ragnar, Schirmer, Henrik, Wilsgaard, Tom, Mathiesen, Ellisiv B., Njølstad, Inger, Løchen, Maja-Lisa, März, Winfried, Kleber, Marcus E., Tomaschitz, Andreas, Grove-Laugesen, Diana, Rejnmark, Lars, Swart, Karin M. A., Brouwer, Ingeborg A., Lips, Paul, van Schoor, Natasja M., Sempos, Christopher T., Durazo-Arvizu, Ramón A., Škrabáková, Zuzana, Dowling, Kirsten G., Cashman, Kevin D., Kiely, Mairead, Pilz, Stefan, Gudnason, Vilmundur, Eiriksdottir, Gudny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356674/
https://www.ncbi.nlm.nih.gov/pubmed/30609725
http://dx.doi.org/10.3390/nu11010074

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