Cargando…

Retinal Neuron Is More Sensitive to Blue Light-Induced Damage than Glia Cell Due to DNA Double-Strand Breaks

Blue light is a major component of visible light and digital displays. Over-exposure to blue light could cause retinal damage. However, the mechanism of its damage is not well defined. Here, we demonstrate that blue light (900 lux) impairs cell viability and induces cell apoptosis in retinal neurocy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Pei, Lai, Zhipeng, Wu, Yihui, Xu, Lijun, Cai, Xiaoxiao, Qiu, Jin, Yang, Panyang, Yang, Meng, Zhou, Pan, Zhuang, Jiejie, Ge, Jian, Yu, Keming, Zhuang, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356720/ https://www.ncbi.nlm.nih.gov/pubmed/30669263 http://dx.doi.org/10.3390/cells8010068

Ejemplares similares

Thrombospondin-1 might be a therapeutic target to suppress RB cells by regulating the DNA double-strand breaks repair
por: Chen, Pei, et al.
Publicado: (2016)

UBE3D Is Involved in Blue Light-Induced Retinal Damage by Regulating Double-Strand Break Repair
por: Xu, Ningda, et al.
Publicado: (2022)

Comparison of the Response to the CXCR4 Antagonist AMD3100 during the Development of Retinal Organoids Derived from ES Cells and Zebrafish Retina
por: Wu, Yihui, et al.
Publicado: (2022)

Gata3 Silencing Is Involved in Neuronal Differentiation and Its Abnormal Expression Impedes Neural Activity in Adult Retinal Neurocytes
por: Chen, Pei, et al.
Publicado: (2022)

More Than Mortar: Glia as Architects of Nervous System Development and Disease
por: Lago-Baldaia, Inês, et al.
Publicado: (2020)

Histone deacetylase inhibitors differentially regulate c-Myc expression in retinoblastoma cells
por: Yu, Na, et al.
Publicado: (2020)

Lithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV
por: Yang, Ying, et al.
Publicado: (2016)

Crx Is Posttranscriptionally Regulated by Light Stimulation in Postnatal Rat Retina
por: Wu, Yihui, et al.
Publicado: (2020)

Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment
por: Chen, Shuilian, et al.
Publicado: (2021)

Fullerol rescues the light-induced retinal damage by modulating Müller glia cell fate
por: Cha, Zhe, et al.
Publicado: (2023)

Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells
por: Li, Liping, et al.
Publicado: (2015)

DNA double-strand breaks in the Toxoplasma gondii-infected cells by the action of reactive oxygen species
por: Zhuang, Haohan, et al.
Publicado: (2020)

Fragile site instability: measuring more than breaks
por: Waisertreiger, Irina, et al.
Publicado: (2020)

BRCA1 Silencing Is Associated with Failure of DNA Repairing in Retinal Neurocytes
por: Chen, Pei, et al.
Publicado: (2014)

Alpha Helices Are More Robust to Mutations than Beta Strands
por: Abrusán, György, et al.
Publicado: (2016)

Brca1 Is Upregulated by 5-Aza-CdR and Promotes DNA Repair and Cell Survival, and Inhibits Neurite Outgrowth in Rat Retinal Neurons
por: Wang, Qiyun, et al.
Publicado: (2018)

Hypermutability of Damaged Single-Strand DNA Formed at Double-Strand Breaks and Uncapped Telomeres in Yeast Saccharomyces cerevisiae
por: Yang, Yong, et al.
Publicado: (2008)

Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template
por: Metzger, Michael J., et al.
Publicado: (2011)

Regulations of Retinal Inflammation: Focusing on Müller Glia
por: Chen, Yingying, et al.
Publicado: (2022)

Brca1 Is Regulated by the Transcription Factor Gata3, and Its Silencing Promotes Neural Differentiation in Retinal Neurons
por: Zhuang, Jiejie, et al.
Publicado: (2022)

More than just Stem Cells: Functional Roles of the Transcription Factor Sox2 in Differentiated Glia and Neurons
por: Mercurio, Sara, et al.
Publicado: (2019)

Commentary: Neochord integrity: More than just initial breaking strength
por: DeCampli, William M.
Publicado: (2021)

MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice
por: Zhang, Houjian, et al.
Publicado: (2023)

THE BLUES AND OLDER MINORITY MUSICIANS: MORE THAN JUST MUSIC XXVI
por: Migliaccio, John N
Publicado: (2019)

The Blues and Older Minority Musicians XXVIII: More Than Just Music
Publicado: (2021)

THE BLUES AND OLDER MINORITY MUSICIANS: MORE THAN JUST MUSIC XXIX
por: Migliaccio, John, et al.
Publicado: (2022)

THE BLUES AND OLDER MINORITY MUSICIANS: MORE THAN JUST MUSIC XXIX
por: Migliaccio, John
Publicado: (2022)

Harnessing the Neuroprotective Behaviors of Müller Glia for Retinal Repair
por: Peña, Juan S., et al.
Publicado: (2022)

Proteins pinpoint double strand breaks
por: Cox, Michael M
Publicado: (2013)

Proliferation Potential of Müller Glia after Retinal Damage Varies between Mouse Strains
por: Suga, Akiko, et al.
Publicado: (2014)

DNA damage signaling in response to double-strand breaks during mitosis
por: Giunta, Simona, et al.
Publicado: (2010)

Processing oxidatively damaged bases at DNA strand breaks by APE1
por: Whitaker, Amy M, et al.
Publicado: (2022)

Deciphering the functional mechanism of zinc ions of PARP1 binding with single strand breaks and double strand breaks
por: Sun, Shuya, et al.
Publicado: (2022)

Repopulated retinal microglia promote Müller glia reprogramming and preserve visual function in retinal degenerative mice
por: Cheng, Xuan, et al.
Publicado: (2023)

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

Retinal Glia Promote Dorsal Root Ganglion Axon Regeneration
por: Lorber, Barbara, et al.
Publicado: (2015)

Müller Glia in Retinal Development: From Specification to Circuit Integration
por: Tworig, Joshua M., et al.
Publicado: (2022)

Translatomic response of retinal Müller glia to acute and chronic stress
por: Chucair-Elliott, Ana J., et al.
Publicado: (2022)

Retinal glia and NF-κB in diabetic retinopathy pathogenesis
por: Park, Susanna S.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_45dkvpst05g6lt0qg75eed08pk