Cargando…
Comprehensive Genomic Profiling Reveals Diverse but Actionable Molecular Portfolios across Hematologic Malignancies: Implications for Next Generation Clinical Trials
Background: The translation of genomic discoveries to the clinic is the cornerstone of precision medicine. However, incorporating next generation sequencing (NGS) of hematologic malignancies into clinical management remains limited. Methods: We describe 235 patients who underwent integrated NGS prof...
Autores principales: | Galanina, Natalie, Bejar, Rafael, Choi, Michael, Goodman, Aaron, Wieduwilt, Matthew, Mulroney, Carolyn, Kim, Lisa, Yeerna, Huwate, Tamayo, Pablo, Vergilio, Jo-Anne, Mughal, Tariq I., Miller, Vincent, Jamieson, Catriona, Kurzrock, Razelle |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356731/ https://www.ncbi.nlm.nih.gov/pubmed/30583461 http://dx.doi.org/10.3390/cancers11010011 |
Ejemplares similares
-
Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immunotherapy
por: Pham, Timothy V., et al.
Publicado: (2020) -
APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy
por: Boichard, Amélie, et al.
Publicado: (2018) -
Remembering the forgotten child: the role of immune checkpoint inhibition in patients with human immunod eficiency virus and cancer
por: Adashek, Jacob J., et al.
Publicado: (2019) -
Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics
por: Cohen, Philip R., et al.
Publicado: (2016) -
Portfolio of Dermochromes
por: Jamieson, W. Allan
Publicado: (1904)