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The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process

Poly(ethylene oxide terephthalate)/poly(butylene terephthalate) (PEOT/PBT) segmented block copolymers are widely used for the manufacturing of 3D-printed bio-scaffolds, due to a combination of several properties, such as cell viability, bio-compatibility, and bio-degradability. Furthermore, they are...

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Autores principales: Vanzanella, Veronica, Scatto, Marco, Zant, Erwin, Sisani, Michele, Bastianini, Maria, Grizzuti, Nino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356737/
https://www.ncbi.nlm.nih.gov/pubmed/30634705
http://dx.doi.org/10.3390/ma12020226
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author Vanzanella, Veronica
Scatto, Marco
Zant, Erwin
Sisani, Michele
Bastianini, Maria
Grizzuti, Nino
author_facet Vanzanella, Veronica
Scatto, Marco
Zant, Erwin
Sisani, Michele
Bastianini, Maria
Grizzuti, Nino
author_sort Vanzanella, Veronica
collection PubMed
description Poly(ethylene oxide terephthalate)/poly(butylene terephthalate) (PEOT/PBT) segmented block copolymers are widely used for the manufacturing of 3D-printed bio-scaffolds, due to a combination of several properties, such as cell viability, bio-compatibility, and bio-degradability. Furthermore, they are characterized by a relatively low viscosity at high temperatures, which is desired during the injection stages of the printing process. At the same time, the microphase separated morphology generated by the demixing of hard and soft segments at intermediate temperatures allows for a quick transition from a liquid-like to a solid-like behavior, thus favoring the shaping and the dimensional stability of the scaffold. In this work, for the first time, the rheology of a commercial PEOT/PBT material is studied over a wide range of temperatures encompassing both the melt state and the phase transition regime. Non-isothermal viscoelastic measurements under oscillatory shear flow allow for a quantitative determination of the material processability in the melt state. Additionally, isothermal experiments below the order–disorder temperature are used to determine the temperature dependence of the phase transition kinetics. The importance of the rheological characterization when designing the 3D-printing scaffold process is also discussed.
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spelling pubmed-63567372019-02-04 The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process Vanzanella, Veronica Scatto, Marco Zant, Erwin Sisani, Michele Bastianini, Maria Grizzuti, Nino Materials (Basel) Article Poly(ethylene oxide terephthalate)/poly(butylene terephthalate) (PEOT/PBT) segmented block copolymers are widely used for the manufacturing of 3D-printed bio-scaffolds, due to a combination of several properties, such as cell viability, bio-compatibility, and bio-degradability. Furthermore, they are characterized by a relatively low viscosity at high temperatures, which is desired during the injection stages of the printing process. At the same time, the microphase separated morphology generated by the demixing of hard and soft segments at intermediate temperatures allows for a quick transition from a liquid-like to a solid-like behavior, thus favoring the shaping and the dimensional stability of the scaffold. In this work, for the first time, the rheology of a commercial PEOT/PBT material is studied over a wide range of temperatures encompassing both the melt state and the phase transition regime. Non-isothermal viscoelastic measurements under oscillatory shear flow allow for a quantitative determination of the material processability in the melt state. Additionally, isothermal experiments below the order–disorder temperature are used to determine the temperature dependence of the phase transition kinetics. The importance of the rheological characterization when designing the 3D-printing scaffold process is also discussed. MDPI 2019-01-10 /pmc/articles/PMC6356737/ /pubmed/30634705 http://dx.doi.org/10.3390/ma12020226 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vanzanella, Veronica
Scatto, Marco
Zant, Erwin
Sisani, Michele
Bastianini, Maria
Grizzuti, Nino
The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process
title The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process
title_full The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process
title_fullStr The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process
title_full_unstemmed The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process
title_short The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process
title_sort rheology of peot/pbt block copolymers in the melt state and in the thermally-induced sol/gel transition implications on the 3d-printing bio-scaffold process
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356737/
https://www.ncbi.nlm.nih.gov/pubmed/30634705
http://dx.doi.org/10.3390/ma12020226
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