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The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process
Poly(ethylene oxide terephthalate)/poly(butylene terephthalate) (PEOT/PBT) segmented block copolymers are widely used for the manufacturing of 3D-printed bio-scaffolds, due to a combination of several properties, such as cell viability, bio-compatibility, and bio-degradability. Furthermore, they are...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356737/ https://www.ncbi.nlm.nih.gov/pubmed/30634705 http://dx.doi.org/10.3390/ma12020226 |
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author | Vanzanella, Veronica Scatto, Marco Zant, Erwin Sisani, Michele Bastianini, Maria Grizzuti, Nino |
author_facet | Vanzanella, Veronica Scatto, Marco Zant, Erwin Sisani, Michele Bastianini, Maria Grizzuti, Nino |
author_sort | Vanzanella, Veronica |
collection | PubMed |
description | Poly(ethylene oxide terephthalate)/poly(butylene terephthalate) (PEOT/PBT) segmented block copolymers are widely used for the manufacturing of 3D-printed bio-scaffolds, due to a combination of several properties, such as cell viability, bio-compatibility, and bio-degradability. Furthermore, they are characterized by a relatively low viscosity at high temperatures, which is desired during the injection stages of the printing process. At the same time, the microphase separated morphology generated by the demixing of hard and soft segments at intermediate temperatures allows for a quick transition from a liquid-like to a solid-like behavior, thus favoring the shaping and the dimensional stability of the scaffold. In this work, for the first time, the rheology of a commercial PEOT/PBT material is studied over a wide range of temperatures encompassing both the melt state and the phase transition regime. Non-isothermal viscoelastic measurements under oscillatory shear flow allow for a quantitative determination of the material processability in the melt state. Additionally, isothermal experiments below the order–disorder temperature are used to determine the temperature dependence of the phase transition kinetics. The importance of the rheological characterization when designing the 3D-printing scaffold process is also discussed. |
format | Online Article Text |
id | pubmed-6356737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-63567372019-02-04 The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process Vanzanella, Veronica Scatto, Marco Zant, Erwin Sisani, Michele Bastianini, Maria Grizzuti, Nino Materials (Basel) Article Poly(ethylene oxide terephthalate)/poly(butylene terephthalate) (PEOT/PBT) segmented block copolymers are widely used for the manufacturing of 3D-printed bio-scaffolds, due to a combination of several properties, such as cell viability, bio-compatibility, and bio-degradability. Furthermore, they are characterized by a relatively low viscosity at high temperatures, which is desired during the injection stages of the printing process. At the same time, the microphase separated morphology generated by the demixing of hard and soft segments at intermediate temperatures allows for a quick transition from a liquid-like to a solid-like behavior, thus favoring the shaping and the dimensional stability of the scaffold. In this work, for the first time, the rheology of a commercial PEOT/PBT material is studied over a wide range of temperatures encompassing both the melt state and the phase transition regime. Non-isothermal viscoelastic measurements under oscillatory shear flow allow for a quantitative determination of the material processability in the melt state. Additionally, isothermal experiments below the order–disorder temperature are used to determine the temperature dependence of the phase transition kinetics. The importance of the rheological characterization when designing the 3D-printing scaffold process is also discussed. MDPI 2019-01-10 /pmc/articles/PMC6356737/ /pubmed/30634705 http://dx.doi.org/10.3390/ma12020226 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Vanzanella, Veronica Scatto, Marco Zant, Erwin Sisani, Michele Bastianini, Maria Grizzuti, Nino The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process |
title | The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process |
title_full | The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process |
title_fullStr | The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process |
title_full_unstemmed | The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process |
title_short | The Rheology of PEOT/PBT Block Copolymers in the Melt State and in the Thermally-Induced Sol/Gel Transition Implications on the 3D-Printing Bio-Scaffold Process |
title_sort | rheology of peot/pbt block copolymers in the melt state and in the thermally-induced sol/gel transition implications on the 3d-printing bio-scaffold process |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356737/ https://www.ncbi.nlm.nih.gov/pubmed/30634705 http://dx.doi.org/10.3390/ma12020226 |
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