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Complement Receptor C5aR1 Inhibition Reduces Pyroptosis in hDPP4-Transgenic Mice Infected with MERS-CoV

Middle East respiratory syndrome coronavirus (MERS-CoV) is a highly pathogenic virus with a crude mortality rate of ~35%. Previously, we established a human DPP4 transgenic (hDPP4-Tg) mouse model in which we studied complement overactivation-induced immunopathogenesis. Here, to better understand the...

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Detalles Bibliográficos
Autores principales:	Jiang, Yuting, Li, Junfeng, Teng, Yue, Sun, Hong, Tian, Guang, He, Lei, Li, Pei, Chen, Yuehong, Guo, Yan, Li, Jiangfan, Zhao, Guangyu, Zhou, Yusen, Sun, Shihui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356766/ https://www.ncbi.nlm.nih.gov/pubmed/30634407 http://dx.doi.org/10.3390/v11010039

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