Cargando…

Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways

Radiotherapy is one of the most common treatment options for local or regional advanced prostate cancer (PCa). Importantly, PCa is prone to radioresistance and often develops into malignancies after long-term radiotherapy. Antrocin, a sesquiterpene lactone isolated from Antrodia cinnamomea, possesse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yu-An, Tzeng, David T. W., Huang, Yi-Ping, Lin, Chun-Jung, Lo, U-Ging, Wu, Chia-Lin, Lin, Ho, Hsieh, Jer-Tsong, Tang, Chih-Hsin, Lai, Chih-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356781/ https://www.ncbi.nlm.nih.gov/pubmed/30602706 http://dx.doi.org/10.3390/cancers11010034

Ejemplares similares

Bacterial Genotoxin-Coated Nanoparticles for Radiotherapy Sensitization in Prostate Cancer
por: Chen, Yu-An, et al.
Publicado: (2021)

Anti-Oxidant, Anti-Mutagenic Activity and Safety Evaluation of Antrocin
por: Su, Yi-Hui, et al.
Publicado: (2023)

Sensitization of Radioresistant Prostate Cancer Cells by Resveratrol Isolated from Arachis hypogaea Stems
por: Chen, Yu-An, et al.
Publicado: (2017)

The regulatory pathways leading to stem-like cells underlie prostate cancer progression
por: Lin, Chun-Jung, et al.
Publicado: (2019)

Multiomics Identification of Potential Targets for Alzheimer Disease and Antrocin as a Therapeutic Candidate
por: Wu, Alexander T. H., et al.
Publicado: (2021)

The role of microRNAs in prostate cancer progression
por: Lo, U-Ging, et al.
Publicado: (2013)

Cytolethal Distending Toxin Enhances Radiosensitivity in Prostate Cancer Cells by Regulating Autophagy
por: Lin, Hwai-Jeng, et al.
Publicado: (2017)

The driver role of JAK‐STAT signalling in cancer stemness capabilities leading to new therapeutic strategies for therapy‐ and castration‐resistant prostate cancer
por: Lo, U‐Ging, et al.
Publicado: (2022)

The evolving landscape of prostate cancer stem cell: Therapeutic implications and future challenges
por: Yun, Eun-Jin, et al.
Publicado: (2016)

Developing New Treatment Options for Castration-Resistant Prostate Cancer and Recurrent Disease
por: Wang, Bo-Ren, et al.
Publicado: (2022)

Impact of cholesterol on disease progression
por: Lin, Chun-Jung, et al.
Publicado: (2015)

Evolving Personalized Therapy for Castration-Resistant Prostate Cancer
por: Liu, Hsin-Ho, et al.
Publicado: (2014)

The roles and mechanism of IFIT5 in bladder cancer epithelial–mesenchymal transition and progression
por: Huang, Jun, et al.
Publicado: (2019)

The paracrine induction of prostate cancer progression by caveolin-1
por: Lin, Chun-Jung, et al.
Publicado: (2019)

RET Regulates Human Medullary Thyroid Cancer Cell Proliferation through CDK5 and STAT3 Activation
por: Yue, Chia-Herng, et al.
Publicado: (2021)

The Role and Mechanism of Epithelial-to-Mesenchymal Transition in Prostate Cancer Progression
por: Lo, U-Ging, et al.
Publicado: (2017)

Synthesis of Natural (−)-Antrocin and Its Enantiomer via Stereoselective Aldol Reaction
por: Angamuthu, Venkatachalam, et al.
Publicado: (2020)

Molecular Mechanisms and Potential Clinical Applications of Campylobacter jejuni Cytolethal Distending Toxin
por: Lai, Cheng-Kuo, et al.
Publicado: (2016)

Simvastatin Sensitizes Radioresistant Prostate Cancer Cells by Compromising DNA Double-Strand Break Repair
por: Chen, Yu-An, et al.
Publicado: (2018)

Future Aspects of CDK5 in Prostate Cancer: From Pathogenesis to Therapeutic Implications
por: Oner, Muhammet, et al.
Publicado: (2019)

Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways
por: Wu, Yu-Jen, et al.
Publicado: (2019)

Editorial: Prognostic Research and Precision Oncology in Upper Tract Urothelial Carcinoma
por: Sheu, Zai-Lin, et al.
Publicado: (2022)

Nanotheranostics With the Combination of Improved Targeting, Therapeutic Effects, and Molecular Imaging
por: Peng, Shin-Lei, et al.
Publicado: (2020)

Sensitization of radio-resistant prostate cancer cells with a unique cytolethal distending toxin
por: Lai, Chih-Ho, et al.
Publicado: (2014)

7‐Epitaxol induces apoptosis in cisplatin‐resistant head and neck squamous cell carcinoma via suppression of AKT and MAPK signalling
por: Yang, Hui‐Ju, et al.
Publicado: (2022)

CCN3 Facilitates Runx2 and Osterix Expression by Inhibiting miR-608 through PI3K/Akt Signaling in Osteoblasts
por: Chen, Po-Chun, et al.
Publicado: (2019)

The network of DAB2IP-miR-138 in regulating drug resistance of renal cell carcinoma associated with stem-like phenotypes
por: Yun, Eun-Jin, et al.
Publicado: (2017)

Japanese encephalitis virus induces matrix metalloproteinase-9 expression via a ROS/c-Src/PDGFR/PI3K/Akt/MAPKs-dependent AP-1 pathway in rat brain astrocytes
por: Yang, Chuen-Mao, et al.
Publicado: (2012)

The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling
por: Shorning, Boris Y., et al.
Publicado: (2020)

Antrodia salmonea Extracts Regulate p53-AR Signaling and Apoptosis in Human Prostate Cancer LNCaP Cells
por: Chen, Chieh-Yin, et al.
Publicado: (2022)

CCN3 promotes epithelial-mesenchymal transition in prostate cancer via FAK/Akt/HIF-1α-induced twist expression
por: Chen, Po-Chun, et al.
Publicado: (2017)

The efficacy of immediate versus delayed antibiotic administration on bacterial growth and biofilm production of selected strains of uropathogenic Escherichia coli and Pseudomonas aeruginosa
por: Gandee, Leah, et al.
Publicado: (2015)

The central role of Sphingosine kinase 1 in the development of neuroendocrine prostate cancer (NEPC): A new targeted therapy of NEPC
por: Lee, Cheng‐Fan, et al.
Publicado: (2022)

Active Targeting of P-Selectin by Fucoidan Modulates the Molecular Profiling of Metastasis in Docetaxel-Resistant Prostate Cancer
por: Ho, Chang-Hsun, et al.
Publicado: (2022)

Adiponectin Induces Oncostatin M Expression in Osteoblasts through the PI3K/Akt Signaling Pathway
por: Su, Chen-Ming, et al.
Publicado: (2015)

Editorial: Prognostic research and precision oncology in upper tract urothelial carcinoma-volume II
por: Yang, Tsung-Mu, et al.
Publicado: (2023)

The Role of PI3K/AKT and MAPK Signaling Pathways in Erythropoietin Signalization
por: Tóthová, Zuzana, et al.
Publicado: (2021)

Adiponectin promotes VEGF-A-dependent angiogenesis in human chondrosarcoma through PI3K, Akt, mTOR, and HIF-α pathway
por: Lee, Hsiang-Ping, et al.
Publicado: (2015)

NGF-trkA signaling modulates the analgesic effects of prostatic acid phosphatase in resiniferatoxin-induced neuropathy
por: Wu, Chieh-Hsin, et al.
Publicado: (2016)

13-Acetoxysarcocrassolide induces apoptosis in human hepatocellular carcinoma cells through mitochondrial dysfunction and suppression of the PI3K/AKT/mTOR/p70S6K signalling pathway
por: Hsu, Chang-Min, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uioketa16mrcosd3o6c9n7dt4k