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Naturally Occurring Mutations within HBV Surface Promoter II Sequences Affect Transcription Activity, HBsAg and HBV DNA Levels in HBeAg-Positive Chronic Hepatitis B Patients

Mutations in hepatitis B virus (HBV) surface promoter II (SPII) have not been well studied in hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) patients. We aimed to investigate SPII mutations in such patients and their biological and clinical impacts. Direct sequencing was used to de...

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Detalles Bibliográficos
Autores principales:	Hao, Ran, Xiang, Kuanhui, Shi, Yan, Zhao, Dong, Tian, Huifang, Xu, Baohong, Zhu, Yufang, Dong, Huan, Ding, Hai, Zhuang, Hui, Hu, Jie, Li, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356792/ https://www.ncbi.nlm.nih.gov/pubmed/30669266 http://dx.doi.org/10.3390/v11010078

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