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Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms
The recombinant antibody fragments generated against the toxic components of scorpion venoms are considered a promising alternative for obtaining new antivenoms for therapy. Using directed evolution and site-directed mutagenesis, it was possible to generate a human single-chain antibody fragment wit...
Autores principales: | Riaño-Umbarila, Lidia, Gómez-Ramírez, Ilse V., Ledezma-Candanoza, Luis M., Olamendi-Portugal, Timoteo, Rodríguez-Rodríguez, Everardo Remi, Fernández-Taboada, Guillermo, Possani, Lourival D., Becerril, Baltazar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356842/ https://www.ncbi.nlm.nih.gov/pubmed/30634620 http://dx.doi.org/10.3390/toxins11010032 |
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