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IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer
Patients with epidermal growth factor receptor (EGFR) mutation-positive lung cancer show a dramatic response to EGFR-tyrosine kinase inhibitors (TKIs). However, acquired drug resistance eventually develops. This study explored the novel mechanisms related to TKI resistance. To identify the genes ass...
Autores principales: | Wu, Shang-Gin, Chang, Tzu-Hua, Tsai, Meng-Feng, Liu, Yi-Nan, Hsu, Chia-Lang, Chang, Yih-Leong, Yu, Chong-Jen, Shih, Jin-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356910/ https://www.ncbi.nlm.nih.gov/pubmed/30609749 http://dx.doi.org/10.3390/cancers11010036 |
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