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Altered VEGF Splicing Isoform Balance in Tumor Endothelium Involves Activation of Splicing Factors Srpk1 and Srsf1 by the Wilms’ Tumor Suppressor Wt1

Angiogenesis is one hallmark of cancer. Vascular endothelial growth factor (VEGF) is a known inducer of angiogenesis. Many patients benefit from antiangiogenic therapies, which however have limitations. Although VEGF is overexpressed in most tumors, different VEGF isoforms with distinct angiogenic p...

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Detalles Bibliográficos
Autores principales:	Wagner, Kay-Dietrich, El Maï, Mounir, Ladomery, Michael, Belali, Tareg, Leccia, Nathalie, Michiels, Jean-François, Wagner, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356959/ https://www.ncbi.nlm.nih.gov/pubmed/30641926 http://dx.doi.org/10.3390/cells8010041

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