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Application of Prostate Cancer Models for Preclinical Study: Advantages and Limitations of Cell Lines, Patient-Derived Xenografts, and Three-Dimensional Culture of Patient-Derived Cells

Various preclinical models have been developed to clarify the pathophysiology of prostate cancer (PCa). Traditional PCa cell lines from clinical metastatic lesions, as exemplified by DU-145, PC-3, and LNCaP cells, are useful tools to define mechanisms underlying tumorigenesis and drug resistance. Ce...

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Detalles Bibliográficos
Autores principales:	Namekawa, Takeshi, Ikeda, Kazuhiro, Horie-Inoue, Kuniko, Inoue, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357050/ https://www.ncbi.nlm.nih.gov/pubmed/30669516 http://dx.doi.org/10.3390/cells8010074

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