Oxidation of Peroxiredoxin 6 in the Presence of GSH Increases its Phospholipase A(2) Activity at Cytoplasmic pH

The expression of the phospholipase A(2) activity (aiPLA(2)) of peroxiredoxin 6 (Prdx6) in the cell cytoplasm is physiologically relevant for the repair of peroxidized cell membranes, but aiPLA(2) assay in vitro indicates that, unlike assay at pH 4, activity at cytosolic pH is essentially absent wit...

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Detalles Bibliográficos
Autores principales: Zhou, Suiping, Dodia, Chandra, Feinstein, Sheldon I., Harper, Sandra, Forman, Henry J., Speicher, David W., Fisher, Aron B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357108/
https://www.ncbi.nlm.nih.gov/pubmed/30586895
http://dx.doi.org/10.3390/antiox8010004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357108/
https://www.ncbi.nlm.nih.gov/pubmed/30586895
http://dx.doi.org/10.3390/antiox8010004

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