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Oxidation of Peroxiredoxin 6 in the Presence of GSH Increases its Phospholipase A(2) Activity at Cytoplasmic pH
The expression of the phospholipase A(2) activity (aiPLA(2)) of peroxiredoxin 6 (Prdx6) in the cell cytoplasm is physiologically relevant for the repair of peroxidized cell membranes, but aiPLA(2) assay in vitro indicates that, unlike assay at pH 4, activity at cytosolic pH is essentially absent wit...
Autores principales: | Zhou, Suiping, Dodia, Chandra, Feinstein, Sheldon I., Harper, Sandra, Forman, Henry J., Speicher, David W., Fisher, Aron B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357108/ https://www.ncbi.nlm.nih.gov/pubmed/30586895 http://dx.doi.org/10.3390/antiox8010004 |
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