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Inhibition of Polyamine Biosynthesis Reverses Ca(2+) Channel Remodeling in Colon Cancer Cells

Store-operated Ca(2+) entry (SOCE) is the most important Ca(2+) entry pathway in non-excitable cells. Colorectal cancer (CRC) shows decreased Ca(2+) store content and enhanced SOCE that correlate with cancer hallmarks and are associated to remodeling of store-operated channels (SOCs). Normal colonic...

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Detalles Bibliográficos
Autores principales: Gutiérrez, Lucía G., Hernández-Morales, Miriam, Núñez, Lucía, Villalobos, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357118/
https://www.ncbi.nlm.nih.gov/pubmed/30642111
http://dx.doi.org/10.3390/cancers11010083