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Detection and Characterization of Enterovirus B73 from a Child in Brazil

Enterovirus B73 is a new member of the Enterovirus B species. First detected in the USA, it has been subsequently identified in China, India, Oman, and the Netherlands. In this study, we characterize the first B73 strain (named TO-127) to be detected in South America. TO-127 was obtained from a chil...

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Autores principales: Ribeiro, Geovani de Oliveira, Luchs, Adriana, Milagres, Flávio Augusto de Pádua, Komninakis, Shirley Vasconcelos, Gill, Danielle Elise, Lobato, Márcia Cristina Alves Brito Sayão, Brustulin, Rafael, Chagas, Rogério Togisaki das, Abrão, Maria de Fátima Neves dos Santos, Soares, Cassia Vitória de Deus Alves, Witkin, Steven S., Villanova, Fabiola, Deng, Xutao, Sabino, Ester Cerdeira, Delwart, Eric, da Costa, Antonio Charlys, Leal, Élcio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357135/
https://www.ncbi.nlm.nih.gov/pubmed/30597828
http://dx.doi.org/10.3390/v11010016
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author Ribeiro, Geovani de Oliveira
Luchs, Adriana
Milagres, Flávio Augusto de Pádua
Komninakis, Shirley Vasconcelos
Gill, Danielle Elise
Lobato, Márcia Cristina Alves Brito Sayão
Brustulin, Rafael
Chagas, Rogério Togisaki das
Abrão, Maria de Fátima Neves dos Santos
Soares, Cassia Vitória de Deus Alves
Witkin, Steven S.
Villanova, Fabiola
Deng, Xutao
Sabino, Ester Cerdeira
Delwart, Eric
da Costa, Antonio Charlys
Leal, Élcio
author_facet Ribeiro, Geovani de Oliveira
Luchs, Adriana
Milagres, Flávio Augusto de Pádua
Komninakis, Shirley Vasconcelos
Gill, Danielle Elise
Lobato, Márcia Cristina Alves Brito Sayão
Brustulin, Rafael
Chagas, Rogério Togisaki das
Abrão, Maria de Fátima Neves dos Santos
Soares, Cassia Vitória de Deus Alves
Witkin, Steven S.
Villanova, Fabiola
Deng, Xutao
Sabino, Ester Cerdeira
Delwart, Eric
da Costa, Antonio Charlys
Leal, Élcio
author_sort Ribeiro, Geovani de Oliveira
collection PubMed
description Enterovirus B73 is a new member of the Enterovirus B species. First detected in the USA, it has been subsequently identified in China, India, Oman, and the Netherlands. In this study, we characterize the first B73 strain (named TO-127) to be detected in South America. TO-127 was obtained from a child with acute gastroenteritis living in a rural area in Northern Brazil. The subject was not infected with any known enteric pathogens such as norovirus, rotavirus, helminths, or enteric bacteria. Analysis of the nearly full-length TO-127 genome (6993 nt) indicated a 74–75% nucleotide similarity with EV-B73 strains from other countries. Evolutionary analysis suggests that B73 is endemic and widespread.
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spelling pubmed-63571352019-02-05 Detection and Characterization of Enterovirus B73 from a Child in Brazil Ribeiro, Geovani de Oliveira Luchs, Adriana Milagres, Flávio Augusto de Pádua Komninakis, Shirley Vasconcelos Gill, Danielle Elise Lobato, Márcia Cristina Alves Brito Sayão Brustulin, Rafael Chagas, Rogério Togisaki das Abrão, Maria de Fátima Neves dos Santos Soares, Cassia Vitória de Deus Alves Witkin, Steven S. Villanova, Fabiola Deng, Xutao Sabino, Ester Cerdeira Delwart, Eric da Costa, Antonio Charlys Leal, Élcio Viruses Brief Report Enterovirus B73 is a new member of the Enterovirus B species. First detected in the USA, it has been subsequently identified in China, India, Oman, and the Netherlands. In this study, we characterize the first B73 strain (named TO-127) to be detected in South America. TO-127 was obtained from a child with acute gastroenteritis living in a rural area in Northern Brazil. The subject was not infected with any known enteric pathogens such as norovirus, rotavirus, helminths, or enteric bacteria. Analysis of the nearly full-length TO-127 genome (6993 nt) indicated a 74–75% nucleotide similarity with EV-B73 strains from other countries. Evolutionary analysis suggests that B73 is endemic and widespread. MDPI 2018-12-28 /pmc/articles/PMC6357135/ /pubmed/30597828 http://dx.doi.org/10.3390/v11010016 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Ribeiro, Geovani de Oliveira
Luchs, Adriana
Milagres, Flávio Augusto de Pádua
Komninakis, Shirley Vasconcelos
Gill, Danielle Elise
Lobato, Márcia Cristina Alves Brito Sayão
Brustulin, Rafael
Chagas, Rogério Togisaki das
Abrão, Maria de Fátima Neves dos Santos
Soares, Cassia Vitória de Deus Alves
Witkin, Steven S.
Villanova, Fabiola
Deng, Xutao
Sabino, Ester Cerdeira
Delwart, Eric
da Costa, Antonio Charlys
Leal, Élcio
Detection and Characterization of Enterovirus B73 from a Child in Brazil
title Detection and Characterization of Enterovirus B73 from a Child in Brazil
title_full Detection and Characterization of Enterovirus B73 from a Child in Brazil
title_fullStr Detection and Characterization of Enterovirus B73 from a Child in Brazil
title_full_unstemmed Detection and Characterization of Enterovirus B73 from a Child in Brazil
title_short Detection and Characterization of Enterovirus B73 from a Child in Brazil
title_sort detection and characterization of enterovirus b73 from a child in brazil
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357135/
https://www.ncbi.nlm.nih.gov/pubmed/30597828
http://dx.doi.org/10.3390/v11010016
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