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Transient Disappearance of RAS Mutant Clones in Plasma: A Counterintuitive Clinical Use of EGFR Inhibitors in RAS Mutant Metastatic Colorectal Cancer
Genomic studies performed through liquid biopsies widely elucidated the evolutionary trajectory of RAS mutant clones under the selective pressure of EGFR inhibitors in patients with wild type RAS primary colorectal tumors. Similarly, the disappearance of RAS mutant clones in plasma has been more rec...
Autores principales: | Raimondi, Cristina, Nicolazzo, Chiara, Belardinilli, Francesca, Loreni, Flavia, Gradilone, Angela, Mahdavian, Yasaman, Gelibter, Alain, Giannini, Giuseppe, Cortesi, Enrico, Gazzaniga, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357143/ https://www.ncbi.nlm.nih.gov/pubmed/30621206 http://dx.doi.org/10.3390/cancers11010042 |
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