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Transient Disappearance of RAS Mutant Clones in Plasma: A Counterintuitive Clinical Use of EGFR Inhibitors in RAS Mutant Metastatic Colorectal Cancer

Genomic studies performed through liquid biopsies widely elucidated the evolutionary trajectory of RAS mutant clones under the selective pressure of EGFR inhibitors in patients with wild type RAS primary colorectal tumors. Similarly, the disappearance of RAS mutant clones in plasma has been more rec...

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Detalles Bibliográficos
Autores principales: Raimondi, Cristina, Nicolazzo, Chiara, Belardinilli, Francesca, Loreni, Flavia, Gradilone, Angela, Mahdavian, Yasaman, Gelibter, Alain, Giannini, Giuseppe, Cortesi, Enrico, Gazzaniga, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357143/
https://www.ncbi.nlm.nih.gov/pubmed/30621206
http://dx.doi.org/10.3390/cancers11010042

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