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Personalized Prediction of Acquired Resistance to EGFR-Targeted Inhibitors Using a Pathway-Based Machine Learning Approach
Epidermal growth factor receptor (EGFR) inhibitors have benefitted cancer patients worldwide, but resistance inevitably develops over time, resulting in treatment failures. An accurate prediction model for acquired resistance (AR) to EGFR inhibitors is critical for early diagnosis and according inte...
Autores principales: | Kim, Young Rae, Kim, Yong Wan, Lee, Suh Eun, Yang, Hye Won, Kim, Sung Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357167/ https://www.ncbi.nlm.nih.gov/pubmed/30621238 http://dx.doi.org/10.3390/cancers11010045 |
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