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The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma

The active form of vitamin B6, pyridoxal phosphate (PLP), is essential for human metabolism. The brain is dependent on vitamin B6 for its neurotransmitter balance. To obtain insight into the genetic determinants of vitamin B6 homeostasis, we conducted a genome-wide association study (GWAS) of the B6...

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Detalles Bibliográficos
Autores principales: Olde Loohuis, Loes M., Albersen, Monique, de Jong, Simone, Wu, Timothy, Luykx, Jurjen J., Jans, Judith J. M., Verhoeven-Duif, Nanda M., Ophoff, Roel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357176/
https://www.ncbi.nlm.nih.gov/pubmed/30583557
http://dx.doi.org/10.3390/genes10010008