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Prostasomes are Pluripotent and Well–Organized Organelles in Human Semen

Prostasomes are submicron, membrane-surrounded organelles produced by the epithelial cells of the human prostate gland and are present in appreciable amounts in normal human semen. The prostasomes are ascribed many functional effects. They have an immunosuppressive capacity by inhibiting the lymphop...

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Detalles Bibliográficos
Autor principal: Gunnar, Ronquist
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Communications and Publications Division (CPD) of the IFCC 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357244/
https://www.ncbi.nlm.nih.gov/pubmed/30720251
Descripción
Sumario:Prostasomes are submicron, membrane-surrounded organelles produced by the epithelial cells of the human prostate gland and are present in appreciable amounts in normal human semen. The prostasomes are ascribed many functional effects. They have an immunosuppressive capacity by inhibiting the lymphoproliferation and the phagocytosis of macrophages. The prostasomes also regulate the complement activation. They possess an antioxidant capacity. The prostasomes are also able to attach onto washed, prostasome-free spermatozoa and promote the forward motility of the sperm cells.