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A graph-based algorithm for estimating clonal haplotypes of tumor sample from sequencing data
BACKGROUND: Haplotype phasing is an important step in many bioinformatics workflows. In cancer genomics, it is suggested that reconstructing the clonal haplotypes of a tumor sample could facilitate a comprehensive understanding of its clonal architecture and further provide valuable reference in cli...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357344/ https://www.ncbi.nlm.nih.gov/pubmed/30704456 http://dx.doi.org/10.1186/s12920-018-0457-4 |