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Predict drug sensitivity of cancer cells with pathway activity inference

BACKGROUND: Predicting cellular responses to drugs has been a major challenge for personalized drug therapy regimen. Recent pharmacogenomic studies measured the sensitivities of heterogeneous cell lines to numerous drugs, and provided valuable data resources to develop and validate computational app...

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Detalles Bibliográficos
Autores principales:	Wang, Xuewei, Sun, Zhifu, Zimmermann, Michael T., Bugrim, Andrej, Kocher, Jean-Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357358/ https://www.ncbi.nlm.nih.gov/pubmed/30704449 http://dx.doi.org/10.1186/s12920-018-0449-4

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