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Opioid response in paediatric cancer patients and the Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene: an Italian study on 87 cancer children and a systematic review

BACKGROUND: Genetic polymorphisms in genes involved in pain modulation have been reported to be associated to opioid efficacy and safety in different clinical settings. METHODS: The association between COMT Val158Met polymorphism (rs4680) and the inter-individual differences in the response to opioi...

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Detalles Bibliográficos
Autores principales:	Lucenteforte, Ersilia, Vannacci, Alfredo, Crescioli, Giada, Lombardi, Niccolò, Vagnoli, Laura, Giunti, Laura, Cetica, Valentina, Coniglio, Maria Luisa, Pugi, Alessandra, Bonaiuti, Roberto, Aricò, Maurizio, Giglio, Sabrina, Messeri, Andrea, Barale, Roberto, Giovannelli, Lisa, Mugelli, Alessandro, Maggini, Valentina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357360/ https://www.ncbi.nlm.nih.gov/pubmed/30704436 http://dx.doi.org/10.1186/s12885-019-5310-4

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