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Integration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma

BACKGROUND: While most pediatric sarcomas respond to front-line therapy, some bone sarcomas do not show radiographic response like soft-tissue sarcomas (rhabdomyosarccomas) but do show 90% necrosis. Though, new therapies are urgently needed to improve survival and quality of life in pediatric patien...

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Detalles Bibliográficos
Autores principales: Cheng, Lijun, Pandya, Pankita H., Liu, Enze, Chandra, Pooja, Wang, Limei, Murray, Mary E., Carter, Jacquelyn, Ferguson, Michael, Saadatzadeh, Mohammad Reza, Bijangi-Visheshsaraei, Khadijeh, Marshall, Mark, Li, Lang, Pollok, Karen E., Renbarger, Jamie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357363/
https://www.ncbi.nlm.nih.gov/pubmed/30704460
http://dx.doi.org/10.1186/s12920-018-0456-5