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Demarcated thresholds of tumor-specific CD8 T cells elicited by MCMV-based vaccine vectors provide robust correlates of protection

BACKGROUND: The capacity of cytomegalovirus (CMV) to elicit long-lasting strong T cell responses, and the ability to engineer the genome of this DNA virus positions CMV-based vaccine vectors highly suitable as a cancer vaccine platform. Defined immune thresholds for tumor protection and the factors...

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Detalles Bibliográficos
Autores principales:	Beyranvand Nejad, Elham, Ratts, Robert B., Panagioti, Eleni, Meyer, Christine, Oduro, Jennifer D., Cicin-Sain, Luka, Früh, Klaus, van der Burg, Sjoerd H., Arens, Ramon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357411/ https://www.ncbi.nlm.nih.gov/pubmed/30704520 http://dx.doi.org/10.1186/s40425-019-0500-9

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